Klebsiella pneumoniae and carbapenemase.

Carbapenems such as imipenem and meropenem, are often used to treat infections caused by extended-spectrum beta-lactamases (ESBLs)-producing Gram-negative bacteria. New class of bacterial enzymes, which means the destruction carbapenems, such as Klebsiella pneumoniae carbapenemases (CP), is increasingly the United States and is reported also in other parts of the world.

KPCS are a class of carbapenemases, which can be stored on transmissible plasmids, all hydrolyze penicillins, cephalosporins and carbapenems are. Options to infections, which are limited due to KPCS to treat and often require the use of polymyxins, fell into oblivion in 1980 for the high rates of nephrotoxicity. Epidemiology of the KPC-producing organisms remains largely unknown and is being intensively studied by the researchers. These objectives are to revise our present understanding of the Communist Party and the main results in an extraordinary meeting of the KPCS in 2008 Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) and Infectious Diseases Society of America (IDSA) joint annual meeting in Washington, DC presented together.